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Computational Biology: Practical [1]

Paper Code: 
DZOL804 P
Credits: 
2
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

DZOL804 P 

 

Computational biology

Practical

 

The students will be able to-

 

CO1: Get hands-on practice of various microscopic techniques oculometry, centrifugation and UV - visible spectroscopy.

CO2: Retrieve information from biological databases along with the submission of sequences into the databases using BLAST & FASTA.

 

Approach in teaching: Discussion, Demonstration, Action Research, Project, Field Trip

Learning activities for the students:Field activities, Simulation, Presentation, Giving task

Class test

Semester end examinations,

 Quiz,

Assignments,

Seminar Presentation

Individual and group projects

 

CONTENTS:
Bioinformatics
Accessing biological databases
Retrieval of nucleotide and protein sequences from the databases.
To perform pair-wise alignment of sequences (BLAST) and interpret the output.
 
Biological tools and techniques
Microscopes
Standardization of Occulometer and measurements of tubular diameter, cell heights.
Measurement of diameter of thyroid follicles.
To study the structure & function of Centrifuge.
To study the principle of UV & visible light spectroscopy
 
Biostatistics
To learn graphical representations of statistical data with the help of computers
(e.g. MS Excel) and bar diagram, frequency polygon, histogram, pie chart.
Hands-on practice of SPSS software.                        
Essential Readings: 
SUGGESTED READINGS
● Ghosh Z and Mallick B. (2008). Bioinformatics: Principles and Applications, Oxford University Press.
● Pevsner J. (2009). Bioinformatics and Functional Genomics, II Edition, Wiley Blackwell.
● Zvelebil, Marketa and Baum O. Jeremy (2008). Understanding Bioinformatics, Garland Science, Taylor and Francis Group, USA.
● Zar, Jerrold H. (1999). Biostatistical Analysis, IV Edition, Pearson Education Inc and Dorling Kindersley Publishing Inc. USA
● Antonisamy, B., Christopher S. and Samuel, P. P. (2010). Biostatistics: Principles and Practice. Tata McGraw Hill Education Private Limited, India.
● Pagana, M. and Gavreau, K. (2000). Principles of Biostatistics, Duxberry Press, USA
● Wilson and Walker. Practical Biochemistry. Cambridge, 2000.
● Cooper. The Cell-A Molecular Approach. ASM, 1997
 
e-RESOURCES:
● e- PGPathshala
 
JOURNALS:
● Journal of Bioinformatics and Computational Biology. ISSN (print): 0219-7200 | ISSN
(online): 1757-6334.
● BMC Bioinformatics, Publisher: BioMed Central ltd. ISSN: 1471-2105.
 
Academic Year: 
2023-2024 [5]

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Source URL: https://www.zoology.iisuniv.ac.in/courses/subjects/computational-biology-practical

Links:
[1] https://www.zoology.iisuniv.ac.in/courses/subjects/computational-biology-practical
[2] https://epgp.inflibnet.ac.in/Home/ViewSubject?catid=2rAs1Puvga4LW93zMe83aA==
[3] https://www.ncbi.nlm.nih.gov/
[4] https://vlab.amrita.edu/index.php?sub=3&brch=311
[5] https://www.zoology.iisuniv.ac.in/academic-year/2023-2024