BIOCHEMISTRY OF METABOLIC PROCESSES

Published on Zoology (https://www.zoology.iisuniv.ac.in)

BIOCHEMISTRY OF METABOLIC PROCESSES [1]

Paper Code:

24CZOL411

Credits:

Contact Hours:

60.00

Max. Marks:

100.00

Objective:

Course objectives:

This course will enable the students to -

1. Differentiate between the structure and function of biomolecules and their role in homeostasis.

2. Acquire knowledge and understanding about enzymes classification, kinetics and factors affecting enzyme activity.

Course Outcomes:

Course

Learning outcomes

(at course level)

Learning and

teaching strategies

Assessment

Strategies

Course Code

Course Title

24CZOL 411

Biochemistry of Metabolic

Processes

CO:73 Develop understanding about carbohydrates types, structure, properties and their metabolic pathways.

CO:74 Explore lipid structure and significance, including metabolic processes.

CO:75 Illustrate amino acids and protein structure, properties, classification and catabolic biochemical processes.

CO:76 Investigate nucleic acid structure, DNA/RNA types, and complementary base pairing.

CO:77 Study enzymes, including their classification, mechanism, kinetics, and regulation.

CO:78 Contribute effectively in course-specific interaction

The approach in teaching:

Lectures,

Discussion, Tutorials, Reading assignments,

Demonstration, Team teaching

Learning activities for the students: Self-learning

assignments, Effective

questions, Simulation,

Seminar presentation,

Giving tasks, Chart preparation

Assessment

Strategies

Continuous assessment, Semester end examinations, Quiz, Solving problems in tutorials, Assignments,

Presentation.

12.00

Unit I:

Carbohydrates

Structure, properties and biological importance:

Monosaccharides, Disaccharides, Polysaccharides and Glycoconjugates

Metabolism- Glycolysis, Krebs cycle, Glycogenesis and glycogenolysis

12.00

Unit II:

Lipids

Structure and Significance:

Physiologically important saturated and unsaturated fatty acids,

Triacylglycerols, Phospholipids, glycolipids, Steroids

Beta oxidation of palmitic acid,

12.00

Unit III:

Proteins

Amino acids: Structure, Classification and General properties of α-amino acids; Physiological importance of essential and non-essential α-amino acids Levels of organization in proteins;

Denaturation;

Introduction to simple and conjugated proteins

Transamination, Deamination, Urea cycle, decarboxylation

12.00

Unit IV:

Nucleic Acids

Structure: Purines and pyrimidines,

Nucleosides, Nucleotides, Nucleic acids

Cot Curves: Base pairing,

Denaturation and Renaturation of DNA

Types of DNA and RNA, Complementarity of DNA

12.00

Unit V:

Enzymes

Nomenclature and classification;

Cofactors; Specificity of enzyme action; Isozymes;

Mechanism of enzyme action; Enzyme kinetics;

Factors affecting rate of enzyme-catalysed reactions;

Derivation of Michaelis-Menten equation, Concept of Km and Vmax,

Essential Readings:

ESSENTIAL READINGS:

● U. Satyanaryana . Biochemistry IV Edition, Elsevier (2013)

● Jain ,J. L. Fundamentals of Biochemistry , S.Chand publishers New Delhi.

● Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.(2007)

● Lehninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors, Shahdara, Delhi.

● Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV Edition. W.H. Freeman and Co

BIOCHEMISTRY OF METABOLIC PROCESSES [1]

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