Molecular Biology & Genetics II

Molecular Biology & Genetics II [1]

Paper Code:

ZOL-202

Credits:

Contact Hours:

45.00

Max. Marks:

100.00

9.00

Nuclear Organization:
Structure & function of nuclear envelope, nuclear matrix and nucleolus
Chromosomes: Morphology, Chromonema, Chromomeres, telomeres, Primary & secondary constrictions, Chromatids
Chromosome type- Polytene & Lampbrush
Chromosomal Organization: euchromatin, Heterochromatin , nucleosome concept

7.00

· DNA structure(A, B, Z type)

· Experiments of Messelson & Stahl

· Replication(Semi-conservative mechanism)

Elementary idea about Polymerases,Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments,

10.00

RNA structure & types( mRNA, rRNA, tRNA)
Transcription(Idea about Polymerases)
Genetic code &

Translation – Basic idea about Protein synthesis

10.00

Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory, Non disjunction in man

Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes

9.00

Mutations- Chromosomal aberrations, Gene mutations

Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis
Human betterment- Eugenics & Euthenics

Essential Readings:

Genetics; Winchester, A. M.; Oxford and IBH Publishing Co.
Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
Genetics; Strickberger W. M.; Prentice Hall of India.
Cell Biology; Powar, C.B; Himalayan Publishing House.
Principles of Genetics; Gardener, E. J.;Wiley eastern, New Delhi.
A Textbook of Genetics; Rastogi, V.B.; Ramnath and Kedarnath
Molecular Biology of the gene; Watson, J.D; Benzamin/ Cummings.
Biochemistry; Voet &Voet; John Wiley & Sons.
Cytology and Genetics. Dyansagar, C.R. Tata McGraw Hill Publ. Co. New Delhi.
Cell Biology : Dyson, R.D. Allen and Bacon, New York.
Cell Biology. Rastogi S.C. : Tata McGraw Hill Publ. Co. New Delhi.
Cell Biology and Genetics. Kohli, S. jain, S. and Ramesh Book Depot. Jaipur.
Cytology : Verma, P.S. and Agrawal V.K : S.Chand and Co. New Delhi.
Genetics. Verma, P.S. and Agrawal V.K. S.Chand and Co., New Delhi.

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